Towards highly seletive cancer treatment: Endogenous lipoprotein-DARPin complexes as a new generation of targeted drug delivery vehicles (DARLINK)
Project objective: The ultimate goal of the project is to develop a new generation of drug vehicles (DARLINK(s)) with a high payload capacity showing a strong potential for high affinity binding to specific receptors on tumor cells. DARLINK can be tailored for mutated cancer cell receptors of individual patients and thus contribute to personalized treatment of cancer.
Principal Investigator: prof. RNDr. Pavol Miškovský, DrSc.
Conversion of integral membrane protein into water soluble form: the case of GPCR
Project objective: The principal goal of this project is to provide „proof of principle“ about possibility to transform of integral membrane protein into its water-soluble analogue. Successful reaching of this goal will provide information and tools for the modification of solubility also others, not only membrane, proteins.
Principal Investigator: doc. RNDr. Erik Sedlák, PhD.
The project 7FP EU (REGPOT) „Fostering Excellence in Multiscale Cell Imaging“ (CELIM) is designed to energize the research potential of the University of P. J. Safarik in Kosice, Slovakia, by the enhancement of the existing network of collaborators with the selected excellent European Partners, centered around the theme of cell imaging, by the acquisition of a new technical infrastructure, and by the reintegration of highly experienced Slovak scientists contemporary working abroad.
Euro‐BioImaging is a large‐scale pan‐European research infrastructure project on the European Strategy Forum on Research Infrastructures (ESFRI) Roadmap. Preparatory Phase of the project lasted from Dec 2010 to May 2014 and was funded by the EC. Euro-BioImaging is now in the interim phase, with representatives of 12 countries and EMBL as international organisation working together towards the implementation of the infrastructure.